Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PCSK1	HGNC:8743 (HGNC) 5122 (Entrez Gene) 162150 (OMIM) PCSK1 (Alliance of Genome Resources)	Chr5 q15	Chr5:96390333-96434143 (-) GRCh38	obesity proprotein convertase 1/3 deficiency	P29120 (UniProt | EBI) NM_000439 (RefSeq)
mouse	Pcsk1	MGI:97511 (MGI) 18548 (Entrez Gene) Gene Tree Pcsk1 (Alliance of Genome Resources)	Chr13 40.63 cM	Chr13:75237945-75282980 (+) GRCm39	endocrine system disease obesity	ENSMUSG00000021587 (Ensembl Gene Model) ENSMUSP00000022075 (Ensembl) ENSMUST00000022075 (Ensembl)
rat	Pcsk1	RGD:3272 (Rat Genome Database) 25204 (Entrez Gene) Pcsk1 (Alliance of Genome Resources)	Chr2 q11			P28840 (UniProt | EBI) NM_017091 (RefSeq)
zebrafish	pcsk1	ZDB-GENE-071009-1 (Zebrafish Model Organism Database) 100005716 (Entrez Gene) pcsk1 (Alliance of Genome Resources)	Chr21			NP_001131134 (RefSeq) NM_001137662 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.