Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	IFNA1	HGNC:5417 (HGNC) 3439 (Entrez Gene) 147660 (OMIM) IFNA1 (Alliance of Genome Resources)	Chr9 p21.3	Chr9:21440439-21441316 (+) GRCh38	Crimean-Congo hemorrhagic fever hepatocellular carcinoma	P01562 (UniProt | EBI) NM_024013 (RefSeq)
	IFNA2	HGNC:5423 (HGNC) 3440 (Entrez Gene) 147562 (OMIM) IFNA2 (Alliance of Genome Resources)	Chr9 p21.3	Chr9:21384255-21385398 (-) GRCh38	common cold hepatitis B hepatocellular carcinoma liver cirrhosis	P01563 (UniProt | EBI) NM_000605 (RefSeq)
	IFNA4	HGNC:5425 (HGNC) 3441 (Entrez Gene) 147564 (OMIM) IFNA4 (Alliance of Genome Resources)	Chr9 p21.3	Chr9:21186618-21187587 (-) GRCh38		P05014 (UniProt | EBI) NM_021068 (RefSeq)
	IFNA5	HGNC:5426 (HGNC) 3442 (Entrez Gene) 147565 (OMIM) IFNA5 (Alliance of Genome Resources)	Chr9 p21.3	Chr9:21304326-21305313 (-) GRCh38		P01569 (UniProt | EBI) NM_002169 (RefSeq)
	IFNA6	HGNC:5427 (HGNC) 3443 (Entrez Gene) 147566 (OMIM) IFNA6 (Alliance of Genome Resources)	Chr9 p21.3	Chr9:21350253-21350956 (-) GRCh38		P05013 (UniProt | EBI) NM_021002 (RefSeq)
	IFNA7	HGNC:5428 (HGNC) 3444 (Entrez Gene) 147567 (OMIM) IFNA7 (Alliance of Genome Resources)	Chr9 p21.3	Chr9:21201469-21202205 (-) GRCh38		P01567 (UniProt | EBI) NM_021057 (RefSeq)
	IFNA8	HGNC:5429 (HGNC) 3445 (Entrez Gene) 147568 (OMIM) IFNA8 (Alliance of Genome Resources)	Chr9 p21.3	Chr9:21409117-21410185 (+) GRCh38		P32881 (UniProt | EBI) NM_002170 (RefSeq)
	IFNA10	HGNC:5418 (HGNC) 3446 (Entrez Gene) 147577 (OMIM) IFNA10 (Alliance of Genome Resources)	Chr9 p21.3	Chr9:21206181-21207143 (-) GRCh38		P01566 (UniProt | EBI) NM_002171 (RefSeq)
	IFNA13	HGNC:5419 (HGNC) 3447 (Entrez Gene) 147578 (OMIM) IFNA13 (Alliance of Genome Resources)	Chr9 p21.3	Chr9:21367372-21368057 (-) GRCh38		P01562 (UniProt | EBI) NM_006900 (RefSeq)
	IFNA14	HGNC:5420 (HGNC) 3448 (Entrez Gene) 147579 (OMIM) IFNA14 (Alliance of Genome Resources)	Chr9 p21.3	Chr9:21239002-21240005 (-) GRCh38		P01570 (UniProt | EBI) NM_002172 (RefSeq)
	IFNA16	HGNC:5421 (HGNC) 3449 (Entrez Gene) 147580 (OMIM) IFNA16 (Alliance of Genome Resources)	Chr9 p21.3	Chr9:21216373-21217311 (-) GRCh38		P05015 (UniProt | EBI) NM_002173 (RefSeq)
	IFNA17	HGNC:5422 (HGNC) 3451 (Entrez Gene) 147583 (OMIM) IFNA17 (Alliance of Genome Resources)	Chr9 p21.3	Chr9:21227243-21228222 (-) GRCh38	Crimean-Congo hemorrhagic fever sarcoidosis	P01571 (UniProt | EBI) NM_021268 (RefSeq)
	IFNA21	HGNC:5424 (HGNC) 3452 (Entrez Gene) 147584 (OMIM) IFNA21 (Alliance of Genome Resources)	Chr9 p21.3	Chr9:21165637-21166660 (-) GRCh38		P01568 (UniProt | EBI) NM_002175 (RefSeq)
mouse	Ifna11	MGI:109210 (MGI) 15964 (Entrez Gene) Gene Tree Ifna11 (Alliance of Genome Resources)	Chr4 42.03 cM	Chr4:88738196-88738768 (+) GRCm39		ENSMUSG00000100549 (Ensembl Gene Model) ENSMUSP00000127921 (Ensembl) ENSMUST00000170428 (Ensembl)
rat	Ifna2	RGD:1311425 (Rat Genome Database) 298213 (Entrez Gene) Ifna2 (Alliance of Genome Resources)	Chr5 q32			NP_001258147 (RefSeq) NM_001271218 (RefSeq)
	Ifna4l1	RGD:6492384 (Rat Genome Database) 100911527 (Entrez Gene) Ifna4l1 (Alliance of Genome Resources)	Chr5			XP_003750010 (RefSeq)
	Ifna5	RGD:1359312 (Rat Genome Database) 298210 (Entrez Gene) Ifna5 (Alliance of Genome Resources)	Chr5 q32			P05011 (UniProt | EBI) NM_001014786 (RefSeq)
	Ifna12l	RGD:1560539 (Rat Genome Database) 502966 (Entrez Gene) Ifna12l (Alliance of Genome Resources)	Chr5 q32			NP_001388886 (RefSeq) NM_001401957 (RefSeq)
	Ifna16l1	RGD:1565225 (Rat Genome Database) 500491 (Entrez Gene) Ifna16l1 (Alliance of Genome Resources)	Chr5 q32			NP_001395778 (RefSeq) NM_001408849 (RefSeq)
	LOC100912314	RGD:6487699 (Rat Genome Database) 100912314 (Entrez Gene) LOC100912314 (Alliance of Genome Resources)	Chr5			XP_063144647 (RefSeq)
	LOC100912356	RGD:6487214 (Rat Genome Database) 100912356 (Entrez Gene) LOC100912356 (Alliance of Genome Resources)	Chr5			NP_001396331 (RefSeq) NM_001409402 (RefSeq)
zebrafish	ifnphi2	ZDB-GENE-071128-1 (Zebrafish Model Organism Database) 100126802 (Entrez Gene) ifnphi2 (Alliance of Genome Resources)	Chr3			NP_001104552 (RefSeq) NM_001111082 (RefSeq)
	ifnphi3	ZDB-GENE-071128-2 (Zebrafish Model Organism Database) 100126803 (Entrez Gene) ifnphi3 (Alliance of Genome Resources)	Chr3			NP_001104553 (RefSeq) NM_001111083 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.