Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	DIS3	HGNC:20604 (HGNC) 22894 (Entrez Gene) 607533 (OMIM) DIS3 (Alliance of Genome Resources)	Chr13 q21.33	Chr13:72752169-72782096 (-) GRCh38		Q9Y2L1 (UniProt | EBI) NM_001322349 (RefSeq)
mouse	Dis3	MGI:1919912 (MGI) 72662 (Entrez Gene) Gene Tree Dis3 (Alliance of Genome Resources)	Chr14 49.25 cM	Chr14:99314070-99337217 (-) GRCm39		72662 (NCBI Gene Model) Q9CSH3 (UniProt | EBI) NM_001360050 (RefSeq)
rat	Dis3	RGD:1304646 (Rat Genome Database) 306103 (Entrez Gene) Dis3 (Alliance of Genome Resources)	Chr15 q21			NP_001120955 (RefSeq) NM_001127483 (RefSeq)
zebrafish	dis3	ZDB-GENE-080213-3 (Zebrafish Model Organism Database) 100003553 (Entrez Gene) dis3 (Alliance of Genome Resources)	Chr1			XP_021326885 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.