Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ADRB3	HGNC:288 (HGNC) 155 (Entrez Gene) 109691 (OMIM) ADRB3 (Alliance of Genome Resources)	Chr8 p11.23	Chr8:37962990-37966599 (-) GRCh38	Alzheimer's disease coronary artery disease diabetic retinopathy dilated cardiomyopathy 1H endometrial cancer gout hypertension metabolic dysfunction-associated steatotic liver disease obesity rheumatoid arthritis type 2 diabetes mellitus	P13945 (UniProt | EBI) NM_000025 (RefSeq)
mouse	Adrb3	MGI:87939 (MGI) 11556 (Entrez Gene) Gene Tree Adrb3 (Alliance of Genome Resources)	Chr8 15.94 cM	Chr8:27715804-27720833 (-) GRCm39		11556 (NCBI Gene Model) P25962 (UniProt | EBI) NM_013462 (RefSeq)
rat	Adrb3	RGD:2061 (Rat Genome Database) 25645 (Entrez Gene) Adrb3 (Alliance of Genome Resources)	Chr16 q12.3			P26255 (UniProt | EBI) NM_013108 (RefSeq)
zebrafish	adrb3a	ZDB-GENE-080917-21 (Zebrafish Model Organism Database) 558248 (Entrez Gene) adrb3a (Alliance of Genome Resources)	Chr8			NP_001121807 (RefSeq) NM_001128335 (RefSeq)
	adrb3b	ZDB-GENE-081022-154 (Zebrafish Model Organism Database) 792519 (Entrez Gene) adrb3b (Alliance of Genome Resources)	Chr10			NP_001128606 (RefSeq) NM_001135134 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.