Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	HTR2C	HGNC:5295 (HGNC) 3358 (Entrez Gene) 312861 (OMIM) HTR2C (Alliance of Genome Resources)	ChrX q23	ChrX:114584078-114910061 (+) GRCh38	bipolar disorder obesity schizophrenia	P28335 (UniProt | EBI) NM_001256761 (RefSeq)
mouse	Htr2c	MGI:96281 (MGI) 15560 (Entrez Gene) Gene Tree Htr2c (Alliance of Genome Resources)	ChrX 68.46 cM	ChrX:145745509-145980273 (+) GRCm39	Prader-Willi syndrome type 2 diabetes mellitus	15560 (NCBI Gene Model) P34968 (UniProt | EBI) NM_008312 (RefSeq)
rat	Htr2c	RGD:2848 (Rat Genome Database) 25187 (Entrez Gene) Htr2c (Alliance of Genome Resources)	ChrX q34			P08909 (UniProt | EBI) NM_012765 (RefSeq)
zebrafish	htr2cl1	ZDB-GENE-081104-48 (Zebrafish Model Organism Database) 100000981 (Entrez Gene) htr2cl1 (Alliance of Genome Resources)	Chr7			NP_001123365 (RefSeq) NM_001129893 (RefSeq)
	htr2cl2	ZDB-GENE-120215-109 (Zebrafish Model Organism Database) 798599 (Entrez Gene) htr2cl2 (Alliance of Genome Resources)	Chr21			XP_001339040 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.