Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	KCNQ5	HGNC:6299 (HGNC) 56479 (Entrez Gene) 607357 (OMIM) KCNQ5 (Alliance of Genome Resources)	Chr6 q13	Chr6:72621792-73198853 (+) GRCh38	autosomal dominant intellectual developmental disorder 46	Q9NR82 (UniProt | EBI) NM_001160134 (RefSeq)
mouse	Kcnq5	MGI:1924937 (MGI) 226922 (Entrez Gene) Gene Tree Kcnq5 (Alliance of Genome Resources)	Chr1 6.67 cM	Chr1:21468627-22032166 (-) GRCm39		ENSMUSG00000028033 (Ensembl Gene Model) ENSMUSP00000110955 (Ensembl) ENSMUST00000115300 (Ensembl)
rat	Kcnq5	RGD:628848 (Rat Genome Database) 259273 (Entrez Gene) Kcnq5 (Alliance of Genome Resources)	Chr9 q13			NP_001128115 (RefSeq) NM_001134643 (RefSeq)
zebrafish	kcnq5a	ZDB-GENE-090312-185 (Zebrafish Model Organism Database) 556841 (Entrez Gene) kcnq5a (Alliance of Genome Resources)	Chr13			XP_021336524 (RefSeq)
	kcnq5b	ZDB-GENE-090312-178 (Zebrafish Model Organism Database) 568646 (Entrez Gene) kcnq5b (Alliance of Genome Resources)	Chr1			XP_021329587 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.