Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	EDN3	HGNC:3178 (HGNC) 1908 (Entrez Gene) 131242 (OMIM) EDN3 (Alliance of Genome Resources)	Chr20 q13.32	Chr20:59300443-59325992 (+) GRCh38	Hirschsprung's disease Waardenburg syndrome Waardenburg syndrome type 4B	P14138 (UniProt | EBI) NM_001424362 (RefSeq)
mouse	Edn3	MGI:95285 (MGI) 13616 (Entrez Gene) Gene Tree Edn3 (Alliance of Genome Resources)	Chr2 98.1 cM	Chr2:174602412-174625835 (+) GRCm39	Hirschsprung's disease Waardenburg syndrome type 4B	13616 (NCBI Gene Model) P48299 (UniProt | EBI) NM_007903 (RefSeq)
rat	Edn3	RGD:2534 (Rat Genome Database) 366270 (Entrez Gene) Edn3 (Alliance of Genome Resources)	Chr3 q43			P13207 (UniProt | EBI) NM_001077650 (RefSeq)
zebrafish	edn3b	ZDB-GENE-090313-235 (Zebrafish Model Organism Database) 100148183 (Entrez Gene) edn3b (Alliance of Genome Resources)	Chr23			NP_001298142 (RefSeq) NM_001311213 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.