Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	APBB2	HGNC:582 (HGNC) 323 (Entrez Gene) 602710 (OMIM) APBB2 (Alliance of Genome Resources)	Chr4 p14-p13	Chr4:40810027-41216714 (-) GRCh38	Alzheimer's disease cognitive disorder	Q92870 (UniProt | EBI) NM_001330658 (RefSeq)
mouse	Apbb2	MGI:108405 (MGI) 11787 (Entrez Gene) Gene Tree Apbb2 (Alliance of Genome Resources)	Chr5 34.43 cM	Chr5:66456046-66776127 (-) GRCm39		ENSMUSG00000029207 (Ensembl Gene Model) ENSMUSP00000123752 (Ensembl) ENSMUST00000162349 (Ensembl)
rat	Apbb2	RGD:1562438 (Rat Genome Database) 305338 (Entrez Gene) Apbb2 (Alliance of Genome Resources)	Chr14 p11			NP_001414394 (RefSeq) NM_001427465 (RefSeq)
zebrafish	apbb2b	ZDB-GENE-090313-73 (Zebrafish Model Organism Database) 564990 (Entrez Gene) apbb2b (Alliance of Genome Resources)	Chr1			XP_068074089 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.