Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ALOX12B	HGNC:430 (HGNC) 242 (Entrez Gene) 603741 (OMIM) ALOX12B (Alliance of Genome Resources)	Chr17 p13.1	Chr17:8072636-8087716 (-) GRCh38	autosomal recessive congenital ichthyosis 2	O75342 (UniProt | EBI) NM_001139 (RefSeq)
mouse	Alox12b	MGI:1274782 (MGI) 11686 (Entrez Gene) Gene Tree Alox12b (Alliance of Genome Resources)	Chr11 42.38 cM	Chr11:69047898-69060617 (+) GRCm39		11686 (NCBI Gene Model) O70582 (UniProt | EBI) NM_009659 (RefSeq)
rat	Alox12b	RGD:1305330 (Rat Genome Database) 287425 (Entrez Gene) Alox12b (Alliance of Genome Resources)	Chr10 q24			Q2KMM4 (UniProt | EBI) NM_001039377 (RefSeq)
zebrafish	si:dkey-17e16.9	ZDB-GENE-091118-123 (Zebrafish Model Organism Database) 794132 (Entrez Gene) si:dkey-17e16.9 (Alliance of Genome Resources)	Chr21			XP_017208558 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.