Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	REEP1	HGNC:25786 (HGNC) 65055 (Entrez Gene) 609139 (OMIM) REEP1 (Alliance of Genome Resources)	Chr2 p11.2	Chr2:86213993-86338083 (-) GRCh38	autosomal dominant distal hereditary motor neuronopathy 12 autosomal recessive distal hereditary motor neuronopathy 6 hereditary spastic paraplegia 31	Q9H902 (UniProt | EBI) NM_001410856 (RefSeq)
mouse	Reep1	MGI:1098827 (MGI) 52250 (Entrez Gene) Gene Tree Reep1 (Alliance of Genome Resources)	Chr6 32.2 cM	Chr6:71684545-71787694 (+) GRCm39	hereditary spastic paraplegia 31	ENSMUSG00000052852 (Ensembl Gene Model) ENSMUSP00000148341 (Ensembl) ENSMUST00000212792 (Ensembl)
rat	Reep1	RGD:1305230 (Rat Genome Database) 362384 (Entrez Gene) Reep1 (Alliance of Genome Resources)	Chr4 q32			NP_001416085 (RefSeq) NM_001429157 (RefSeq)
zebrafish	reep1	ZDB-GENE-110411-267 (Zebrafish Model Organism Database) 799901 (Entrez Gene) reep1 (Alliance of Genome Resources)	Chr17			XP_021323143 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.