Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CFI	HGNC:5394 (HGNC) 3426 (Entrez Gene) 217030 (OMIM) CFI (Alliance of Genome Resources)	Chr4 q25	Chr4:109730982-109802150 (-) GRCh38	age related macular degeneration 13 atypical hemolytic-uremic syndrome complement factor I deficiency Kuhnt-Junius degeneration macular degeneration	P05156 (UniProt | EBI) NM_001375278 (RefSeq)
mouse	Cfi	MGI:105937 (MGI) 12630 (Entrez Gene) Gene Tree Cfi (Alliance of Genome Resources)	Chr3 59.21 cM	Chr3:129630432-129668978 (+) GRCm39	glomerulonephritis	12630 (NCBI Gene Model) Q61129 (UniProt | EBI) NM_001409673 (RefSeq)
rat	Cfi	RGD:620429 (Rat Genome Database) 79126 (Entrez Gene) Cfi (Alliance of Genome Resources)	Chr2 q43			Q9WUW3 (UniProt | EBI) NM_024157 (RefSeq)
zebrafish	cfi	ZDB-GENE-110922-7 (Zebrafish Model Organism Database) 557557 (Entrez Gene) cfi (Alliance of Genome Resources)	Chr23			XP_017209949 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.