Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	IKZF1	HGNC:13176 (HGNC) 10320 (Entrez Gene) 603023 (OMIM) IKZF1 (Alliance of Genome Resources)	Chr7 p12.2	Chr7:50303455-50405101 (+) GRCh38	acute lymphoblastic leukemia B-lymphoblastic leukemia/lymphoma colorectal cancer common variable immunodeficiency 13	Q13422 (UniProt | EBI) NM_001220765 (RefSeq)
mouse	Ikzf1	MGI:1342540 (MGI) 22778 (Entrez Gene) Gene Tree Ikzf1 (Alliance of Genome Resources)	Chr11 7.02 cM	Chr11:11634980-11722926 (+) GRCm39		ENSMUSG00000018654 (Ensembl Gene Model) ENSMUSP00000067372 (Ensembl) ENSMUST00000065433 (Ensembl)
rat	Ikzf1	RGD:1562979 (Rat Genome Database) 305501 (Entrez Gene) Ikzf1 (Alliance of Genome Resources)	Chr14 q21			NP_001100707 (RefSeq) NM_001107237 (RefSeq)
zebrafish	ikzf1	ZDB-GENE-980526-304 (Zebrafish Model Organism Database) 30177 (Entrez Gene) ikzf1 (Alliance of Genome Resources)	Chr13			NP_571061 (RefSeq) NM_130986 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.