Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	WNT2	HGNC:12780 (HGNC) 7472 (Entrez Gene) 147870 (OMIM) WNT2 (Alliance of Genome Resources)	Chr7 q31.2	Chr7:117275451-117323152 (-) GRCh38	breast carcinoma hepatocellular carcinoma urinary system cancer	P09544 (UniProt | EBI) NM_003391 (RefSeq)
mouse	Wnt2	MGI:98954 (MGI) 22413 (Entrez Gene) Gene Tree Wnt2 (Alliance of Genome Resources)	Chr6 8.08 cM	Chr6:17988939-18030584 (-) GRCm39		ENSMUSG00000010797 (Ensembl Gene Model) ENSMUSP00000010941 (Ensembl) ENSMUST00000010941 (Ensembl)
rat	Wnt2	RGD:621346 (Rat Genome Database) 114487 (Entrez Gene) Wnt2 (Alliance of Genome Resources)	Chr4 q22			NP_446147 (RefSeq) NM_053695 (RefSeq)
zebrafish	wnt2	ZDB-GENE-980526-416 (Zebrafish Model Organism Database) 30127 (Entrez Gene) wnt2 (Alliance of Genome Resources)	Chr18			Q92048 (UniProt | EBI) NM_130950 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.