Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	NRAS	HGNC:7989 (HGNC) 4893 (Entrez Gene) 164790 (OMIM) NRAS (Alliance of Genome Resources)	Chr1 p13.2	Chr1:114704469-114716771 (-) GRCh38	acute lymphoblastic leukemia acute myeloid leukemia autoimmune lymphoproliferative syndrome type 4 colorectal cancer epidermal nevus glioblastoma hepatocellular carcinoma large congenital melanocytic nevus linear nevus sebaceous syndrome melanoma multiple myeloma myelodysplastic syndrome Noonan syndrome 6 papillary thyroid carcinoma	P01111 (UniProt | EBI) NM_002524 (RefSeq)
mouse	Nras	MGI:97376 (MGI) 18176 (Entrez Gene) Gene Tree Nras (Alliance of Genome Resources)	Chr3 45.25 cM	Chr3:102965643-102975230 (+) GRCm39		18176 (NCBI Gene Model) P08556 (UniProt | EBI) NM_001410509 (RefSeq)
rat	Nras	RGD:3205 (Rat Genome Database) 24605 (Entrez Gene) Nras (Alliance of Genome Resources)	Chr2 q34			Q04970 (UniProt | EBI) NM_080766 (RefSeq)
zebrafish	nras	ZDB-GENE-990415-166 (Zebrafish Model Organism Database) 30380 (Entrez Gene) nras (Alliance of Genome Resources)	Chr8			P79737 (UniProt | EBI) NM_131145 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.