Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	LEF1	HGNC:6551 (HGNC) 51176 (Entrez Gene) 153245 (OMIM) LEF1 (Alliance of Genome Resources)	Chr4 q25	Chr4:108047545-108168956 (-) GRCh38	ovarian cancer	Q9UJU2 (UniProt | EBI) NM_001166119 (RefSeq)
mouse	Lef1	MGI:96770 (MGI) 16842 (Entrez Gene) Gene Tree Lef1 (Alliance of Genome Resources)	Chr3 60.78 cM	Chr3:130904120-131018005 (+) GRCm39		ENSMUSG00000027985 (Ensembl Gene Model) ENSMUSP00000029611 (Ensembl) ENSMUST00000029611 (Ensembl)
rat	Lef1	RGD:620241 (Rat Genome Database) 161452 (Entrez Gene) Lef1 (Alliance of Genome Resources)	Chr2 q43			Q9QXN1 (UniProt | EBI) NM_130429 (RefSeq)
zebrafish	lef1	ZDB-GENE-990714-26 (Zebrafish Model Organism Database) 30701 (Entrez Gene) lef1 (Alliance of Genome Resources)	Chr1			NP_571501 (RefSeq) NM_131426 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.