Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PDHA1	HGNC:8806 (HGNC) 5160 (Entrez Gene) 300502 (OMIM) PDHA1 (Alliance of Genome Resources)	ChrX p22.12	ChrX:19343893-19361718 (+) GRCh38	pyruvate decarboxylase deficiency	P08559 (UniProt | EBI) NM_001173456 (RefSeq)
mouse	Pdha1	MGI:97532 (MGI) 18597 (Entrez Gene) Gene Tree Pdha1 (Alliance of Genome Resources)	ChrX 73.95 cM	ChrX:158905205-158921409 (-) GRCm39		ENSMUSG00000031299 (Ensembl Gene Model) ENSMUSP00000033662 (Ensembl) ENSMUST00000033662 (Ensembl)
rat	Pdha1	RGD:3286 (Rat Genome Database) 29554 (Entrez Gene) Pdha1 (Alliance of Genome Resources)	ChrX q14			P26284 (UniProt | EBI) NM_001004072 (RefSeq)
	Pdha1l1	RGD:1590190 (Rat Genome Database) 685778 (Entrez Gene) Pdha1l1 (Alliance of Genome Resources)	Chr16 q12.5
zebrafish	pdha1a	ZDB-GENE-040426-2719 (Zebrafish Model Organism Database) 406702 (Entrez Gene) pdha1a (Alliance of Genome Resources)	Chr5			NP_998558 (RefSeq) NM_213393 (RefSeq)
	pdha1b	ZDB-GENE-040718-96 (Zebrafish Model Organism Database) 436672 (Entrez Gene) pdha1b (Alliance of Genome Resources)	Chr24			NP_001002399 (RefSeq) NM_001002399 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.