Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	FLT4	HGNC:3767 (HGNC) 2324 (Entrez Gene) 136352 (OMIM) FLT4 (Alliance of Genome Resources)	Chr5 q35.3	Chr5:180601506-180650298 (-) GRCh38	hereditary lymphedema IA	P35916 (UniProt | EBI) NM_001354989 (RefSeq)
mouse	Flt4	MGI:95561 (MGI) 14257 (Entrez Gene) Gene Tree Flt4 (Alliance of Genome Resources)	Chr11 29.69 cM	Chr11:49500506-49543566 (+) GRCm39	hereditary lymphedema	14257 (NCBI Gene Model) P35917 (UniProt | EBI) NM_008029 (RefSeq)
rat	Flt4	RGD:621737 (Rat Genome Database) 114110 (Entrez Gene) Flt4 (Alliance of Genome Resources)	Chr10 q21			Q91ZT1 (UniProt | EBI) NM_053652 (RefSeq)
zebrafish	flt4	ZDB-GENE-980526-326 (Zebrafish Model Organism Database) 30121 (Entrez Gene) flt4 (Alliance of Genome Resources)	Chr14			Q5MD89 (UniProt | EBI) NM_130945 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.