Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	KLF4	HGNC:6348 (HGNC) 9314 (Entrez Gene) 602253 (OMIM) KLF4 (Alliance of Genome Resources)	Chr9 q31.2	Chr9:107484852-107490482 (-) GRCh38	hepatocellular carcinoma	O43474 (UniProt | EBI) NM_004235 (RefSeq)
mouse	Klf4	MGI:1342287 (MGI) 16600 (Entrez Gene) Gene Tree Klf4 (Alliance of Genome Resources)	Chr4 29.76 cM	Chr4:55527143-55532466 (-) GRCm39		ENSMUSG00000003032 (Ensembl Gene Model) ENSMUSP00000103245 (Ensembl) ENSMUST00000107619 (Ensembl)
rat	Klf4	RGD:621445 (Rat Genome Database) 114505 (Entrez Gene) Klf4 (Alliance of Genome Resources)	Chr5 q24			NP_446165 (RefSeq) NM_053713 (RefSeq)
zebrafish	klf4	ZDB-GENE-111014-1 (Zebrafish Model Organism Database) 562155 (Entrez Gene) klf4 (Alliance of Genome Resources)	Chr21			NP_001106955 (RefSeq) NM_001113483 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.