Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	KDM5B	HGNC:18039 (HGNC) 10765 (Entrez Gene) 605393 (OMIM) KDM5B (Alliance of Genome Resources)	Chr1 q32.1	Chr1:202724495-202808487 (-) GRCh38	autosomal recessive intellectual developmental disorder 65 breast cancer high grade glioma	Q9UGL1 (UniProt | EBI) NM_001347591 (RefSeq)
mouse	Kdm5b	MGI:1922855 (MGI) 75605 (Entrez Gene) Gene Tree Kdm5b (Alliance of Genome Resources)	Chr1 58.24 cM	Chr1:134487916-134560621 (+) GRCm39		75605 (NCBI Gene Model) Q80Y84 (UniProt | EBI) NM_152895 (RefSeq)
rat	Kdm5b	RGD:1565602 (Rat Genome Database) 304809 (Entrez Gene) Kdm5b (Alliance of Genome Resources)	Chr13 q13			NP_001100647 (RefSeq) NM_001107177 (RefSeq)
zebrafish	kdm5ba	ZDB-GENE-030131-5379 (Zebrafish Model Organism Database) 327168 (Entrez Gene) kdm5ba (Alliance of Genome Resources)	Chr11			NP_001334536 (RefSeq) NM_001128327 (RefSeq)
	kdm5bb	ZDB-GENE-030424-1 (Zebrafish Model Organism Database) 415256 (Entrez Gene) kdm5bb (Alliance of Genome Resources)	Chr8			Q6IQX0 (UniProt | EBI) NM_001002166 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.