Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	IL1A	HGNC:5991 (HGNC) 3552 (Entrez Gene) 147760 (OMIM) IL1A (Alliance of Genome Resources)	Chr2 q14.1	Chr2:112773925-112784493 (-) GRCh38	acute myeloid leukemia Alzheimer's disease asthma autoimmune thrombocytopenic purpura end stage renal disease Fabry disease graft-versus-host disease interstitial lung disease iridocyclitis juvenile rheumatoid arthritis keratoconus lung non-small cell carcinoma multiple myeloma osteoporosis pulmonary fibrosis rheumatoid arthritis Schnitzler syndrome type 1 diabetes mellitus	P01583 (UniProt | EBI) NM_000575 (RefSeq)
mouse	Il1a	MGI:96542 (MGI) 16175 (Entrez Gene) Gene Tree Il1a (Alliance of Genome Resources)	Chr2 62.9 cM	Chr2:129141530-129151892 (-) GRCm39		16175 (NCBI Gene Model) P01582 (UniProt | EBI) NM_010554 (RefSeq)
rat	Il1a	RGD:2890 (Rat Genome Database) 24493 (Entrez Gene) Il1a (Alliance of Genome Resources)	Chr3 q36			P16598 (UniProt | EBI) NM_017019 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.