Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	KLKB1	HGNC:6371 (HGNC) 3818 (Entrez Gene) 229000 (OMIM) KLKB1 (Alliance of Genome Resources)	Chr4 q35.2	Chr4:186210853-186258471 (+) GRCh38	lupus nephritis systemic lupus erythematosus	P03952 (UniProt | EBI) NM_000892 (RefSeq)
mouse	Klkb1	MGI:102849 (MGI) 16621 (Entrez Gene) Gene Tree Klkb1 (Alliance of Genome Resources)	Chr8 25.17 cM	Chr8:45719725-45747872 (-) GRCm39		16621 (NCBI Gene Model) P26262 (UniProt | EBI) NM_008455 (RefSeq)
rat	Klkb1	RGD:67382 (Rat Genome Database) 25048 (Entrez Gene) Klkb1 (Alliance of Genome Resources)	Chr16 q11			P14272 (UniProt | EBI) NM_012725 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.