Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	MMP12	HGNC:7158 (HGNC) 4321 (Entrez Gene) 601046 (OMIM) MMP12 (Alliance of Genome Resources)	Chr11 q22.2	Chr11:102862736-102874982 (-) GRCh38	abdominal aortic aneurysm arteriosclerosis Barrett's esophagus coronary aneurysm coronary artery disease esophagus adenocarcinoma multiple sclerosis	P39900 (UniProt | EBI) NM_002426 (RefSeq)
mouse	Mmp12	MGI:97005 (MGI) 17381 (Entrez Gene) Gene Tree Mmp12 (Alliance of Genome Resources)	Chr9 2.46 cM	Chr9:7344397-7360461 (+) GRCm39		17381 (NCBI Gene Model) P34960 (UniProt | EBI) NM_001320076 (RefSeq)
rat	Mmp12	RGD:620195 (Rat Genome Database) 117033 (Entrez Gene) Mmp12 (Alliance of Genome Resources)	Chr8 q11			Q63341 (UniProt | EBI) NM_053963 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.