Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PDE9A	HGNC:8795 (HGNC) 5152 (Entrez Gene) 602973 (OMIM) PDE9A (Alliance of Genome Resources)	Chr21 q22.3	Chr21:42653621-42775509 (+) GRCh38		O76083 (UniProt | EBI) NM_001315533 (RefSeq)
mouse	Pde9a	MGI:1277179 (MGI) 18585 (Entrez Gene) Gene Tree Pde9a (Alliance of Genome Resources)	Chr17 16.23 cM	Chr17:31605184-31695284 (+) GRCm39		ENSMUSG00000041119 (Ensembl Gene Model) ENSMUSP00000038005 (Ensembl) ENSMUST00000047168 (Ensembl)
rat	Pde9a	RGD:621035 (Rat Genome Database) 191569 (Entrez Gene) Pde9a (Alliance of Genome Resources)	Chr20 p12			Q8QZV1 (UniProt | EBI) NM_138543 (RefSeq)
zebrafish	pde9aa	ZDB-GENE-130920-1 (Zebrafish Model Organism Database) 799942 (Entrez Gene) pde9aa (Alliance of Genome Resources)	Chr9			XP_021334564 (RefSeq)
	pde9ab	ZDB-GENE-210629-1 (Zebrafish Model Organism Database) 571737 (Entrez Gene) pde9ab (Alliance of Genome Resources)	Chr5			XP_700447 (RefSeq)
	pde9ac	ZDB-GENE-130530-807 (Zebrafish Model Organism Database) 564389 (Entrez Gene) pde9ac (Alliance of Genome Resources)	Chr15			XP_692819 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.