Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TBX2	HGNC:11597 (HGNC) 6909 (Entrez Gene) 600747 (OMIM) TBX2 (Alliance of Genome Resources)	Chr17 q23.2	Chr17:61399843-61409466 (+) GRCh38	atrial heart septal defect heart septal defect vertebral anomalies and variable endocrine and T-cell dysfunction	Q13207 (UniProt | EBI) NM_005994 (RefSeq)
mouse	Tbx2	MGI:98494 (MGI) 21385 (Entrez Gene) Gene Tree Tbx2 (Alliance of Genome Resources)	Chr11 51.34 cM	Chr11:85723441-85732774 (+) GRCm39		21385 (NCBI Gene Model) Q60707 (UniProt | EBI) NM_009324 (RefSeq)
rat	Tbx2	RGD:1311014 (Rat Genome Database) 303398 (Entrez Gene) Tbx2 (Alliance of Genome Resources)	Chr10 q26			NP_001388735 (RefSeq) NM_001401806 (RefSeq)
zebrafish	tbx2a	ZDB-GENE-990917-4 (Zebrafish Model Organism Database) 573084 (Entrez Gene) tbx2a (Alliance of Genome Resources)	Chr5			NP_001095854 (RefSeq) NM_001102384 (RefSeq)
	tbx2b	ZDB-GENE-990726-27 (Zebrafish Model Organism Database) 30253 (Entrez Gene) tbx2b (Alliance of Genome Resources)	Chr15			Q7ZTU9 (UniProt | EBI) NM_131051 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.