Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TWIST1	HGNC:12428 (HGNC) 7291 (Entrez Gene) 601622 (OMIM) TWIST1 (Alliance of Genome Resources)	Chr7 p21.1	Chr7:19020991-19117636 (-) GRCh38	acrocephalosyndactylia breast cancer breast carcinoma craniosynostosis Saethre-Chotzen syndrome Sweeney-Cox syndrome	Q15672 (UniProt | EBI) NM_000474 (RefSeq)
mouse	Twist1	MGI:98872 (MGI) 22160 (Entrez Gene) Gene Tree Twist1 (Alliance of Genome Resources)	Chr12 14.81 cM	Chr12:34007670-34009828 (+) GRCm39	Saethre-Chotzen syndrome	ENSMUSG00000035799 (Ensembl Gene Model) ENSMUSP00000040089 (Ensembl) ENSMUST00000049089 (Ensembl)
rat	Twist1	RGD:621455 (Rat Genome Database) 85489 (Entrez Gene) Twist1 (Alliance of Genome Resources)	Chr6 q16			NP_445982 (RefSeq) NM_053530 (RefSeq)
zebrafish	twist1a	ZDB-GENE-000210-6 (Zebrafish Model Organism Database) 30175 (Entrez Gene) twist1a (Alliance of Genome Resources)	Chr19			NP_571059 (RefSeq) NM_130984 (RefSeq)
	twist1b	ZDB-GENE-050417-357 (Zebrafish Model Organism Database) 550518 (Entrez Gene) twist1b (Alliance of Genome Resources)	Chr16			NP_001017820 (RefSeq) NM_001017820 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.