Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	NOTCH2	HGNC:7882 (HGNC) 4853 (Entrez Gene) 600275 (OMIM) NOTCH2 (Alliance of Genome Resources)	Chr1 p12	Chr1:119911553-120100779 (-) GRCh38	Alagille syndrome Hajdu-Cheney syndrome	Q04721 (UniProt | EBI) NM_001200001 (RefSeq)
mouse	Notch2	MGI:97364 (MGI) 18129 (Entrez Gene) Gene Tree Notch2 (Alliance of Genome Resources)	Chr3 42.42 cM	Chr3:97920854-98057683 (+) GRCm39	Hajdu-Cheney syndrome pre-eclampsia	18129 (NCBI Gene Model) O35516 (UniProt | EBI) NM_010928 (RefSeq)
rat	Notch2	RGD:3188 (Rat Genome Database) 29492 (Entrez Gene) Notch2 (Alliance of Genome Resources)	Chr2 q34			Q9QW30 (UniProt | EBI) NM_024358 (RefSeq)
zebrafish	notch2	ZDB-GENE-000329-4 (Zebrafish Model Organism Database) 58065 (Entrez Gene) notch2 (Alliance of Genome Resources)	Chr8			NP_001108566 (RefSeq) NM_001115094 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.