Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CDC25C	HGNC:1727 (HGNC) 995 (Entrez Gene) 157680 (OMIM) CDC25C (Alliance of Genome Resources)	Chr5 q31.2	Chr5:138285265-138338355 (-) GRCh38	endometrial cancer prostate cancer	P30307 (UniProt | EBI) NM_001364027 (RefSeq)
mouse	Cdc25c	MGI:88350 (MGI) 12532 (Entrez Gene) Gene Tree Cdc25c (Alliance of Genome Resources)	Chr18 18.71 cM	Chr18:34866046-34884586 (-) GRCm39		ENSMUSG00000044201 (Ensembl Gene Model) ENSMUSP00000055427 (Ensembl) ENSMUST00000060710 (Ensembl)
rat	Cdc25c	RGD:1311875 (Rat Genome Database) 307511 (Entrez Gene) Cdc25c (Alliance of Genome Resources)	Chr18 p12			NP_001388252 (RefSeq) NM_001107396 (RefSeq)
zebrafish	cdc25b	ZDB-GENE-000330-5 (Zebrafish Model Organism Database) 57925 (Entrez Gene) cdc25b (Alliance of Genome Resources)	Chr13			NP_001108567 (RefSeq) NM_001115095 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.