Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CDC25A	HGNC:1725 (HGNC) 993 (Entrez Gene) 116947 (OMIM) CDC25A (Alliance of Genome Resources)	Chr3 p21.31	Chr3:48157146-48188417 (-) GRCh38	cervical cancer prostate cancer urinary bladder cancer	P30304 (UniProt | EBI) NM_001789 (RefSeq)
mouse	Cdc25a	MGI:103198 (MGI) 12530 (Entrez Gene) Gene Tree Cdc25a (Alliance of Genome Resources)	Chr9 59.81 cM	Chr9:109704647-109722963 (+) GRCm39		ENSMUSG00000032477 (Ensembl Gene Model) ENSMUSP00000091882 (Ensembl) ENSMUST00000094324 (Ensembl)
rat	Cdc25a	RGD:621498 (Rat Genome Database) 171102 (Entrez Gene) Cdc25a (Alliance of Genome Resources)	Chr8 q32			P48965 (UniProt | EBI) NM_133571 (RefSeq)
zebrafish	cdc25b	ZDB-GENE-000330-5 (Zebrafish Model Organism Database) 57925 (Entrez Gene) cdc25b (Alliance of Genome Resources)	Chr13			NP_001108567 (RefSeq) NM_001115095 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.