Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	BAX	HGNC:959 (HGNC) 581 (Entrez Gene) 600040 (OMIM) BAX (Alliance of Genome Resources)	Chr19 q13.33	Chr19:48954815-48961798 (+) GRCh38	acute lymphoblastic leukemia ataxia telangiectasia colon adenocarcinoma colorectal cancer	Q07812 (UniProt | EBI) NM_001291430 (RefSeq)
mouse	Bax	MGI:99702 (MGI) 12028 (Entrez Gene) Gene Tree Bax (Alliance of Genome Resources)	Chr7 29.32 cM	Chr7:45111121-45116322 (-) GRCm39		ENSMUSG00000003873 (Ensembl Gene Model) ENSMUSP00000033093 (Ensembl) ENSMUST00000033093 (Ensembl)
rat	Bax	RGD:2192 (Rat Genome Database) 24887 (Entrez Gene) Bax (Alliance of Genome Resources)	Chr1 q22			Q63690 (UniProt | EBI) NM_017059 (RefSeq)
zebrafish	baxa	ZDB-GENE-000511-6 (Zebrafish Model Organism Database) 58081 (Entrez Gene) baxa (Alliance of Genome Resources)	Chr3			NP_571637 (RefSeq) NM_131562 (RefSeq)
	baxb	ZDB-GENE-050227-21 (Zebrafish Model Organism Database) 503609 (Entrez Gene) baxb (Alliance of Genome Resources)	Chr3			NP_001013314 (RefSeq) NM_001013296 (RefSeq)
	zgc:153993	ZDB-GENE-060929-176 (Zebrafish Model Organism Database) 767645 (Entrez Gene) zgc:153993 (Alliance of Genome Resources)	Chr7			NP_001070053 (RefSeq) NM_001076585 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.