Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	KRT74	HGNC:28929 (HGNC) 121391 (Entrez Gene) 608248 (OMIM) KRT74 (Alliance of Genome Resources)	Chr12 q13.13	Chr12:52565782-52573843 (-) GRCh38	autosomal dominant woolly hair ectodermal dysplasia 7 hypotrichosis 3	Q7RTS7 (UniProt | EBI) NM_175053 (RefSeq)
mouse	Krt74	MGI:3629975 (MGI) 406222 (Entrez Gene) Gene Tree Krt74 (Alliance of Genome Resources)	Chr15 57.01 cM	Chr15:101662787-101671873 (-) GRCm39		ENSMUSG00000067596 (Ensembl Gene Model) Q6IFZ9 (UniProt | EBI) ENSMUST00000229279 (Ensembl)
zebrafish	krt4	ZDB-GENE-000607-83 (Zebrafish Model Organism Database) 794486 (Entrez Gene) krt4 (Alliance of Genome Resources)	Chr6			NP_571584 (RefSeq) NM_131509 (RefSeq)
	krt5	ZDB-GENE-991110-23 (Zebrafish Model Organism Database) 797351 (Entrez Gene) krt5 (Alliance of Genome Resources)	Chr23			NP_571231 (RefSeq) NM_131156 (RefSeq)
	zgc:158846	ZDB-GENE-070209-50 (Zebrafish Model Organism Database) 100009654 (Entrez Gene) zgc:158846 (Alliance of Genome Resources)	Chr6			NP_001076492 (RefSeq) NM_001083023 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.