Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SPTB	HGNC:11274 (HGNC) 6710 (Entrez Gene) 182870 (OMIM) SPTB (Alliance of Genome Resources)	Chr14 q23.3	Chr14:64746283-64879907 (-) GRCh38	hereditary spherocytosis hereditary spherocytosis type 2	P11277 (UniProt | EBI) NM_001355436 (RefSeq)
mouse	Sptb	MGI:98387 (MGI) 20741 (Entrez Gene) Gene Tree Sptb (Alliance of Genome Resources)	Chr12 33.73 cM	Chr12:76627262-76757321 (-) GRCm39		20741 (NCBI Gene Model) P15508 (UniProt | EBI) NM_013675 (RefSeq)
rat	Sptb	RGD:1303243 (Rat Genome Database) 314251 (Entrez Gene) Sptb (Alliance of Genome Resources)	Chr6 q24			NP_001420901 (RefSeq) NM_001433972 (RefSeq)
zebrafish	sptb	ZDB-GENE-000906-1 (Zebrafish Model Organism Database) 58040 (Entrez Gene) sptb (Alliance of Genome Resources)	Chr17			NP_571600 (RefSeq) NM_131525 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.