Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	NTRK2	HGNC:8032 (HGNC) 4915 (Entrez Gene) 600456 (OMIM) NTRK2 (Alliance of Genome Resources)	Chr9 q21.33	Chr9:84668375-85095751 (+) GRCh38	Alzheimer's disease autistic disorder developmental and epileptic encephalopathy 58 major depressive disorder morbid obesity	Q16620 (UniProt | EBI) NM_001369550 (RefSeq)
mouse	Ntrk2	MGI:97384 (MGI) 18212 (Entrez Gene) Gene Tree Ntrk2 (Alliance of Genome Resources)	Chr13 31.2 cM	Chr13:58954383-59281784 (+) GRCm39		ENSMUSG00000055254 (Ensembl Gene Model) ENSMUSP00000078757 (Ensembl) ENSMUST00000079828 (Ensembl)
rat	Ntrk2	RGD:3213 (Rat Genome Database) 25054 (Entrez Gene) Ntrk2 (Alliance of Genome Resources)	Chr17 p14			Q63604 (UniProt | EBI) NM_012731 (RefSeq)
zebrafish	ntrk2a	ZDB-GENE-010126-1 (Zebrafish Model Organism Database) 65090 (Entrez Gene) ntrk2a (Alliance of Genome Resources)	Chr8			NP_001353483 (RefSeq) NM_001366554 (RefSeq)
	ntrk2b	ZDB-GENE-010126-2 (Zebrafish Model Organism Database) 570240 (Entrez Gene) ntrk2b (Alliance of Genome Resources)	Chr5			NP_001184090 (RefSeq) NM_001197161 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.