Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PRSS1	HGNC:9475 (HGNC) 5644 (Entrez Gene) 276000 (OMIM) PRSS1 (Alliance of Genome Resources)	Chr7 q34	Chr7:142749468-142753072 (+) GRCh38	pancreatitis	P07477 (UniProt | EBI) NM_002769 (RefSeq)
	PRSS2	HGNC:9483 (HGNC) 5645 (Entrez Gene) 601564 (OMIM) PRSS2 (Alliance of Genome Resources)	Chr7 q34	Chr7:142760398-142774564 (+) GRCh38		P07478 (UniProt | EBI) NM_002770 (RefSeq)
	PRSS3P2	HGNC:43788 (HGNC) 154754 (Entrez Gene) PRSS3P2 (Alliance of Genome Resources)	Chr7 q34			Q8NHM4 (UniProt | EBI) NM_139000 (RefSeq)
mouse	Try10	MGI:3687012 (MGI) 436522 (Entrez Gene) Gene Tree Try10 (Alliance of Genome Resources)	Chr6 19.48 cM	Chr6:41331039-41334848 (+) GRCm39		ENSMUSG00000071521 (Ensembl Gene Model) ENSMUSP00000071976 (Ensembl) ENSMUST00000072103 (Ensembl)
rat	Prss3	RGD:1311446 (Rat Genome Database) 362347 (Entrez Gene) Prss3 (Alliance of Genome Resources)	Chr4 q23			NP_001102096 (RefSeq) NM_001108626 (RefSeq)
	Try5	RGD:1560283 (Rat Genome Database) 103690254 (Entrez Gene) Try5 (Alliance of Genome Resources)	Chr4			XP_008761147 (RefSeq)
zebrafish	prss1	ZDB-GENE-010131-7 (Zebrafish Model Organism Database) 65223 (Entrez Gene) prss1 (Alliance of Genome Resources)	Chr16			NP_571783 (RefSeq) NM_131708 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.