Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	MAP2K6	HGNC:6846 (HGNC) 5608 (Entrez Gene) 601254 (OMIM) MAP2K6 (Alliance of Genome Resources)	Chr17 q24.3	Chr17:69414697-69553865 (+) GRCh38	cervical cancer ovarian carcinoma Pick's disease progressive supranuclear palsy restrictive cardiomyopathy	P52564 (UniProt | EBI) NM_002758 (RefSeq)
mouse	Map2k6	MGI:1346870 (MGI) 26399 (Entrez Gene) Gene Tree Map2k6 (Alliance of Genome Resources)	Chr11 73.6 cM	Chr11:110289948-110416348 (+) GRCm39		ENSMUSG00000020623 (Ensembl Gene Model) ENSMUSP00000020949 (Ensembl) ENSMUST00000020949 (Ensembl)
rat	Map2k6	RGD:620666 (Rat Genome Database) 114495 (Entrez Gene) Map2k6 (Alliance of Genome Resources)	Chr10 q32.1			NP_446155 (RefSeq) NM_053703 (RefSeq)
zebrafish	map2k6	ZDB-GENE-010202-3 (Zebrafish Model Organism Database) 65239 (Entrez Gene) map2k6 (Alliance of Genome Resources)	Chr12			Q9DGE0 (UniProt | EBI) NM_001312870 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.