Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	HMGA1	HGNC:5010 (HGNC) 3159 (Entrez Gene) 600701 (OMIM) HMGA1 (Alliance of Genome Resources)	Chr6 p21.31	Chr6:34236873-34246231 (+) GRCh38	type 2 diabetes mellitus	P17096 (UniProt | EBI) NM_145901 (RefSeq)
mouse	Hmga1	MGI:96160 (MGI) 15361 (Entrez Gene) Gene Tree Hmga1 (Alliance of Genome Resources)	Chr17 14.5 cM	Chr17:27775471-27782648 (+) GRCm39	lymphoma T-cell acute lymphoblastic leukemia type 2 diabetes mellitus uterine cancer	ENSMUSG00000046711 (Ensembl Gene Model) ENSMUSP00000155966 (Ensembl) ENSMUST00000231866 (Ensembl)
rat	Hmga1	RGD:628699 (Rat Genome Database) 117062 (Entrez Gene) Hmga1 (Alliance of Genome Resources)	Chr20 p12			Q8K585 (UniProt | EBI) NM_139327 (RefSeq)
	Hmga1l1	RGD:1564836 (Rat Genome Database) 302676 (Entrez Gene) Hmga1l1 (Alliance of Genome Resources)	ChrX q14			XP_228930 (RefSeq)
zebrafish	hmga1a	ZDB-GENE-010502-1 (Zebrafish Model Organism Database) 406447 (Entrez Gene) hmga1a (Alliance of Genome Resources)	Chr23			NP_998333 (RefSeq) NM_001289906 (RefSeq)
	hmga1b	ZDB-GENE-061013-204 (Zebrafish Model Organism Database) 768130 (Entrez Gene) hmga1b (Alliance of Genome Resources)	Chr6			NP_001070744 (RefSeq) NM_001077276 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.