Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	IGF1	HGNC:5464 (HGNC) 3479 (Entrez Gene) 147440 (OMIM) IGF1 (Alliance of Genome Resources)	Chr12 q23.2	Chr12:102395874-102481839 (-) GRCh38	acne Alzheimer's disease brain ischemia diabetic retinopathy dilated cardiomyopathy Huntington's disease microcephaly myocardial infarction myopia pancreatic cancer type 1 diabetes mellitus type 2 diabetes mellitus	P05019 (UniProt | EBI) NM_001111285 (RefSeq)
mouse	Igf1	MGI:96432 (MGI) 16000 (Entrez Gene) Gene Tree Igf1 (Alliance of Genome Resources)	Chr10 43.7 cM	Chr10:87694127-87772904 (+) GRCm39		ENSMUSG00000020053 (Ensembl Gene Model) ENSMUSP00000056668 (Ensembl) ENSMUST00000062862 (Ensembl)
rat	Igf1	RGD:2868 (Rat Genome Database) 24482 (Entrez Gene) Igf1 (Alliance of Genome Resources)	Chr7 q13			P08025 (UniProt | EBI) NM_001082477 (RefSeq)
zebrafish	igf1	ZDB-GENE-010607-2 (Zebrafish Model Organism Database) 114433 (Entrez Gene) igf1 (Alliance of Genome Resources)	Chr4			NP_571900 (RefSeq) NM_131825 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.