Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	GJA8	HGNC:4281 (HGNC) 2703 (Entrez Gene) 600897 (OMIM) GJA8 (Alliance of Genome Resources)	Chr1 q21.2	Chr1:147902795-147914486 (+) GRCh38	cataract cataract 1 multiple types	P48165 (UniProt | EBI) NM_005267 (RefSeq)
mouse	Gja8	MGI:99953 (MGI) 14616 (Entrez Gene) Gene Tree Gja8 (Alliance of Genome Resources)	Chr3 Syntenic	Chr3:96820882-96833336 (-) GRCm39	cataract 1 multiple types	ENSMUSG00000049908 (Ensembl Gene Model) ENSMUSP00000049532 (Ensembl) ENSMUST00000062944 (Ensembl)
rat	Gja8	RGD:628890 (Rat Genome Database) 29601 (Entrez Gene) Gja8 (Alliance of Genome Resources)	Chr2			Q8K4Q9 (UniProt | EBI) NM_153465 (RefSeq)
zebrafish	gja8a	ZDB-GENE-050616-14 (Zebrafish Model Organism Database) 569409 (Entrez Gene) gja8a (Alliance of Genome Resources)	Chr9			NP_001121822 (RefSeq) NM_001128350 (RefSeq)
	gja8b	ZDB-GENE-010607-3 (Zebrafish Model Organism Database) 114403 (Entrez Gene) gja8b (Alliance of Genome Resources)	Chr1			NP_571884 (RefSeq) NM_131809 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.