Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TNFRSF10A	HGNC:11904 (HGNC) 8797 (Entrez Gene) 603611 (OMIM) TNFRSF10A (Alliance of Genome Resources)	Chr8 p21.3	Chr8:23190452-23225102 (-) GRCh38	cervical cancer esophagus adenocarcinoma head and neck squamous cell carcinoma mantle cell lymphoma multiple myeloma renal cell carcinoma urinary bladder cancer	O00220 (UniProt | EBI) NM_003844 (RefSeq)
	TNFRSF10B	HGNC:11905 (HGNC) 8795 (Entrez Gene) 603612 (OMIM) TNFRSF10B (Alliance of Genome Resources)	Chr8 p21.3	Chr8:23020133-23069031 (-) GRCh38	head and neck squamous cell carcinoma	O14763 (UniProt | EBI) NM_003842 (RefSeq)
	TNFRSF10C	HGNC:11906 (HGNC) 8794 (Entrez Gene) 603613 (OMIM) TNFRSF10C (Alliance of Genome Resources)	Chr8 p21.3	Chr8:23102921-23117445 (+) GRCh38		O14798 (UniProt | EBI) NM_003841 (RefSeq)
	TNFRSF10D	HGNC:11907 (HGNC) 8793 (Entrez Gene) 603614 (OMIM) TNFRSF10D (Alliance of Genome Resources)	Chr8 p21.3	Chr8:23135588-23164027 (-) GRCh38		Q9UBN6 (UniProt | EBI) NM_003840 (RefSeq)
mouse	Tnfrsf10b	MGI:1341090 (MGI) 21933 (Entrez Gene) Gene Tree Tnfrsf10b (Alliance of Genome Resources)	Chr14 36.1 cM	Chr14:70004921-70021860 (+) GRCm39		21933 (NCBI Gene Model) Q9QZM4 (UniProt | EBI) NM_020275 (RefSeq)
rat	Tnfrsf10b	RGD:1308041 (Rat Genome Database) 364420 (Entrez Gene) Tnfrsf10b (Alliance of Genome Resources)	Chr15 p11			NP_001382649 (RefSeq) NM_001395720 (RefSeq)
zebrafish	hdr	ZDB-GENE-030826-5 (Zebrafish Model Organism Database) 373093 (Entrez Gene) hdr (Alliance of Genome Resources)	Chr5			NP_919372 (RefSeq) NM_194391 (RefSeq)
	tnfrsfa	ZDB-GENE-010802-1 (Zebrafish Model Organism Database) 114461 (Entrez Gene) tnfrsfa (Alliance of Genome Resources)	Chr21			NP_571915 (RefSeq) NM_131840 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.