Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TFE3	HGNC:11752 (HGNC) 7030 (Entrez Gene) 314310 (OMIM) TFE3 (Alliance of Genome Resources)	ChrX p11.23	ChrX:49028726-49043410 (-) GRCh38	renal cell carcinoma	P19532 (UniProt | EBI) NM_001282142 (RefSeq)
mouse	Tfe3	MGI:98511 (MGI) 209446 (Entrez Gene) Gene Tree Tfe3 (Alliance of Genome Resources)	ChrX 3.5 cM	ChrX:7628799-7641441 (+) GRCm39		ENSMUSG00000000134 (Ensembl Gene Model) ENSMUSP00000076864 (Ensembl) ENSMUST00000077680 (Ensembl)
rat	Tfe3	RGD:1559642 (Rat Genome Database) 317376 (Entrez Gene) Tfe3 (Alliance of Genome Resources)	ChrX q12			NP_001258156 (RefSeq) NM_001271227 (RefSeq)
zebrafish	tfe3a	ZDB-GENE-010919-2 (Zebrafish Model Organism Database) 114834 (Entrez Gene) tfe3a (Alliance of Genome Resources)	Chr8			NP_571923 (RefSeq) NM_131848 (RefSeq)
	tfe3b	ZDB-GENE-010919-3 (Zebrafish Model Organism Database) 564996 (Entrez Gene) tfe3b (Alliance of Genome Resources)	Chr11			NP_001038531 (RefSeq) NM_001045066 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.