Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TPI1	HGNC:12009 (HGNC) 7167 (Entrez Gene) 190450 (OMIM) TPI1 (Alliance of Genome Resources)	Chr12 p13.31	Chr12:6867119-6870948 (+) GRCh38	carbohydrate metabolic disorder triosephosphate isomerase deficiency	P60174 (UniProt | EBI) NM_001258026 (RefSeq)
mouse	Tpi1	MGI:98797 (MGI) 21991 (Entrez Gene) Gene Tree Tpi1 (Alliance of Genome Resources)	Chr6 59.17 cM	Chr6:124787549-124791121 (-) GRCm39	triosephosphate isomerase deficiency	21991 (NCBI Gene Model) P17751 (UniProt | EBI) NM_009415 (RefSeq)
rat	Tpi1	RGD:3896 (Rat Genome Database) 24849 (Entrez Gene) Tpi1 (Alliance of Genome Resources)	Chr4 q42			P48500 (UniProt | EBI) NM_022922 (RefSeq)
	Tpi1l1	RGD:1560534 (Rat Genome Database) 500959 (Entrez Gene) Tpi1l1 (Alliance of Genome Resources)	Chr8 q13			NP_001028244 (RefSeq) NM_001033072 (RefSeq)
zebrafish	tpi1a	ZDB-GENE-020416-3 (Zebrafish Model Organism Database) 192309 (Entrez Gene) tpi1a (Alliance of Genome Resources)	Chr19			Q1MTI4 (UniProt | EBI) NM_153667 (RefSeq)
	tpi1b	ZDB-GENE-020416-4 (Zebrafish Model Organism Database) 560753 (Entrez Gene) tpi1b (Alliance of Genome Resources)	Chr16			Q90XG0 (UniProt | EBI) NM_153668 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.