Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ACVRL1	HGNC:175 (HGNC) 94 (Entrez Gene) 601284 (OMIM) ACVRL1 (Alliance of Genome Resources)	Chr12 q13.13	Chr12:51906908-51923361 (+) GRCh38	hereditary hemorrhagic telangiectasia pulmonary hypertension	P37023 (UniProt | EBI) NM_000020 (RefSeq)
mouse	Acvrl1	MGI:1338946 (MGI) 11482 (Entrez Gene) Gene Tree Acvrl1 (Alliance of Genome Resources)	Chr15 56.41 cM	Chr15:101026403-101043217 (+) GRCm39	arteriovenous malformations of the brain hereditary hemorrhagic telangiectasia	11482 (NCBI Gene Model) Q61288 (UniProt | EBI) NM_001277255 (RefSeq)
rat	Acvrl1	RGD:2029 (Rat Genome Database) 25237 (Entrez Gene) Acvrl1 (Alliance of Genome Resources)	Chr7 q36			P80203 (UniProt | EBI) NM_022441 (RefSeq)
zebrafish	acvrl1	ZDB-GENE-021003-1 (Zebrafish Model Organism Database) 266753 (Entrez Gene) acvrl1 (Alliance of Genome Resources)	Chr23			NP_705929 (RefSeq) NM_153643 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.