Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PLK1	HGNC:9077 (HGNC) 5347 (Entrez Gene) 602098 (OMIM) PLK1 (Alliance of Genome Resources)	Chr16 p12.2	Chr16:23677656-23690367 (+) GRCh38	urinary bladder cancer	P53350 (UniProt | EBI) NM_005030 (RefSeq)
mouse	Plk1	MGI:97621 (MGI) 18817 (Entrez Gene) Gene Tree Plk1 (Alliance of Genome Resources)	Chr7 65.52 cM	Chr7:121758662-121769096 (+) GRCm39		ENSMUSG00000030867 (Ensembl Gene Model) ENSMUSP00000033154 (Ensembl) ENSMUST00000033154 (Ensembl)
rat	Plk1	RGD:3352 (Rat Genome Database) 25515 (Entrez Gene) Plk1 (Alliance of Genome Resources)	Chr1 q36			Q62673 (UniProt | EBI) NM_017100 (RefSeq)
zebrafish	plk1	ZDB-GENE-021115-7 (Zebrafish Model Organism Database) 280649 (Entrez Gene) plk1 (Alliance of Genome Resources)	Chr1			NP_001003890 (RefSeq) NM_001003890 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.