Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	HNF1A	HGNC:11621 (HGNC) 6927 (Entrez Gene) 142410 (OMIM) HNF1A (Alliance of Genome Resources)	Chr12 q24.31	Chr12:120978543-121002512 (+) GRCh38	cerebral infarction colorectal cancer coronary artery disease familial hepatic adenoma gestational diabetes glucose intolerance hepatocellular adenoma hepatocellular carcinoma maturity-onset diabetes of the young maturity-onset diabetes of the young type 3 pre-eclampsia renal cell carcinoma type 1 diabetes mellitus type 1 diabetes mellitus 20 type 2 diabetes mellitus	P20823 (UniProt | EBI) NM_001406915 (RefSeq)
mouse	Hnf1a	MGI:98504 (MGI) 21405 (Entrez Gene) Gene Tree Hnf1a (Alliance of Genome Resources)	Chr5 55.99 cM	Chr5:115087039-115109121 (-) GRCm39	maturity-onset diabetes of the young type 3 phenylketonuria type 2 diabetes mellitus	21405 (NCBI Gene Model) P22361 (UniProt | EBI) NM_009327 (RefSeq)
rat	Hnf1a	RGD:3828 (Rat Genome Database) 24817 (Entrez Gene) Hnf1a (Alliance of Genome Resources)	Chr12 q16			P15257 (UniProt | EBI) NM_012669 (RefSeq)
zebrafish	hnf1a	ZDB-GENE-021206-12 (Zebrafish Model Organism Database) 266961 (Entrez Gene) hnf1a (Alliance of Genome Resources)	Chr8			NP_739570 (RefSeq) NM_170764 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.