Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	POLA1	HGNC:9173 (HGNC) 5422 (Entrez Gene) 312040 (OMIM) POLA1 (Alliance of Genome Resources)	ChrX p22.11-p21.3	ChrX:24693873-24996986 (+) GRCh38	Van Esch-O'Driscoll syndrome X-linked reticulate pigmentary disorder	P09884 (UniProt | EBI) NM_001330360 (RefSeq)
mouse	Pola1	MGI:99660 (MGI) 18968 (Entrez Gene) Gene Tree Pola1 (Alliance of Genome Resources)	ChrX 41.06 cM	ChrX:92348373-92675761 (-) GRCm39		ENSMUSG00000006678 (Ensembl Gene Model) ENSMUSP00000006856 (Ensembl) ENSMUST00000006856 (Ensembl)
rat	Pola1	RGD:621816 (Rat Genome Database) 85241 (Entrez Gene) Pola1 (Alliance of Genome Resources)	ChrX q22			O89042 (UniProt | EBI) NM_053479 (RefSeq)
zebrafish	pola1	ZDB-GENE-030114-9 (Zebrafish Model Organism Database) 317740 (Entrez Gene) pola1 (Alliance of Genome Resources)	Chr24			NP_001292393 (RefSeq) NM_001305464 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.