Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ESR2	HGNC:3468 (HGNC) 2100 (Entrez Gene) 601663 (OMIM) ESR2 (Alliance of Genome Resources)	Chr14 q23.2-q23.3	Chr14:64084232-64338613 (-) GRCh38	alopecia Alzheimer's disease breast cancer colorectal cancer coronary artery disease Graves' disease hypertension hypospadias osteoarthritis osteoporosis ovarian dysgenesis 8 Parkinson's disease pre-eclampsia primary open angle glaucoma prostate cancer rheumatoid arthritis systemic lupus erythematosus	Q92731 (UniProt | EBI) NM_001040275 (RefSeq)
mouse	Esr2	MGI:109392 (MGI) 13983 (Entrez Gene) Gene Tree Esr2 (Alliance of Genome Resources)	Chr12 33.52 cM	Chr12:76167193-76224033 (-) GRCm39		13983 (NCBI Gene Model) O08537 (UniProt | EBI) NM_207707 (RefSeq)
rat	Esr2	RGD:2582 (Rat Genome Database) 25149 (Entrez Gene) Esr2 (Alliance of Genome Resources)	Chr6 q24			Q62986 (UniProt | EBI) NM_012754 (RefSeq)
zebrafish	esr2a	ZDB-GENE-030116-2 (Zebrafish Model Organism Database) 317734 (Entrez Gene) esr2a (Alliance of Genome Resources)	Chr20			NP_851297 (RefSeq) NM_180966 (RefSeq)
	esr2b	ZDB-GENE-030116-1 (Zebrafish Model Organism Database) 317733 (Entrez Gene) esr2b (Alliance of Genome Resources)	Chr13			NP_777287 (RefSeq) NM_174862 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.