Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ZNF423	HGNC:16762 (HGNC) 23090 (Entrez Gene) 604557 (OMIM) ZNF423 (Alliance of Genome Resources)	Chr16 q12.1	Chr16:49487524-49859279 (-) GRCh38	nephronophthisis 14	Q2M1K9 (UniProt | EBI) NM_001330533 (RefSeq)
mouse	Zfp423	MGI:1891217 (MGI) 94187 (Entrez Gene) Gene Tree Zfp423 (Alliance of Genome Resources)	Chr8 42.29 cM	Chr8:88388438-88686223 (-) GRCm39	cerebellar disease Dandy-Walker syndrome	ENSMUSG00000045333 (Ensembl Gene Model) ENSMUSP00000105282 (Ensembl) ENSMUST00000109655 (Ensembl)
rat	Zfp423	RGD:621664 (Rat Genome Database) 94188 (Entrez Gene) Zfp423 (Alliance of Genome Resources)	Chr19 p11			O08961 (UniProt | EBI) NM_053583 (RefSeq)
zebrafish	znf423	ZDB-GENE-030131-4368 (Zebrafish Model Organism Database) 566696 (Entrez Gene) znf423 (Alliance of Genome Resources)	Chr18			A1L1R6 (UniProt | EBI) NM_001080030 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.