Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	DENND5B	HGNC:28338 (HGNC) 160518 (Entrez Gene) 617279 (OMIM) DENND5B (Alliance of Genome Resources)	Chr12 p11.21	Chr12:31382226-31591136 (-) GRCh38		Q6ZUT9 (UniProt | EBI) NM_001366890 (RefSeq)
mouse	Dennd5b	MGI:2444273 (MGI) 320560 (Entrez Gene) Gene Tree Dennd5b (Alliance of Genome Resources)	Chr6 78.71 cM	Chr6:148889569-149003178 (-) GRCm39		ENSMUSG00000030313 (Ensembl Gene Model) ENSMUSP00000107182 (Ensembl) ENSMUST00000111557 (Ensembl)
rat	Dennd5b	RGD:2318606 (Rat Genome Database) 100365679 (Entrez Gene) Dennd5b (Alliance of Genome Resources)	Chr4			NP_001418889 (RefSeq) NM_001431962 (RefSeq)
zebrafish	dennd5b	ZDB-GENE-030131-2248 (Zebrafish Model Organism Database) 323528 (Entrez Gene) dennd5b (Alliance of Genome Resources)	Chr4			Q6NXD8 (UniProt | EBI) NM_212644 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.