Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	BRD4	HGNC:13575 (HGNC) 23476 (Entrez Gene) 608749 (OMIM) BRD4 (Alliance of Genome Resources)	Chr19 p13.12	Chr19:15235519-15332545 (-) GRCh38	colon cancer Cornelia de Lange syndrome 6 idiopathic pulmonary fibrosis	O60885 (UniProt | EBI) NM_058243 (RefSeq)
mouse	Brd4	MGI:1888520 (MGI) 57261 (Entrez Gene) Gene Tree Brd4 (Alliance of Genome Resources)	Chr17 17.39 cM	Chr17:32415248-32503696 (-) GRCm39	nephrocalcinosis	ENSMUSG00000024002 (Ensembl Gene Model) ENSMUSP00000003726 (Ensembl) ENSMUST00000003726 (Ensembl)
rat	Brd4	RGD:1307282 (Rat Genome Database) 362844 (Entrez Gene) Brd4 (Alliance of Genome Resources)	Chr7 q11			NP_001094373 (RefSeq) NM_001100903 (RefSeq)
zebrafish	brd4	ZDB-GENE-030131-267 (Zebrafish Model Organism Database) 570531 (Entrez Gene) brd4 (Alliance of Genome Resources)	Chr3			F1R5H6 (UniProt | EBI) NM_001111281 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.