Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PLEKHM1	HGNC:29017 (HGNC) 9842 (Entrez Gene) 611466 (OMIM) PLEKHM1 (Alliance of Genome Resources)	Chr17 q21.31	Chr17:45434209-45490758 (-) GRCh38	autosomal recessive osteopetrosis 6 osteopetrosis	Q9Y4G2 (UniProt | EBI) NM_014798 (RefSeq)
mouse	Plekhm1	MGI:2443207 (MGI) 353047 (Entrez Gene) Gene Tree Plekhm1 (Alliance of Genome Resources)	Chr11 67.09 cM	Chr11:103255101-103303513 (-) GRCm39	autosomal recessive osteopetrosis 6	ENSMUSG00000034247 (Ensembl Gene Model) ENSMUSP00000047327 (Ensembl) ENSMUST00000041272 (Ensembl)
rat	Plekhm1	RGD:1308010 (Rat Genome Database) 303584 (Entrez Gene) Plekhm1 (Alliance of Genome Resources)	Chr10 q32.1			Q5PQS0 (UniProt | EBI) NM_001009677 (RefSeq)
zebrafish	plekhm1	ZDB-GENE-030131-2752 (Zebrafish Model Organism Database) 564048 (Entrez Gene) plekhm1 (Alliance of Genome Resources)	Chr12			NP_001314781 (RefSeq) NM_001089403 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.