Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ARRB2	HGNC:712 (HGNC) 409 (Entrez Gene) 107941 (OMIM) ARRB2 (Alliance of Genome Resources)	Chr17 p13.2	Chr17:4710596-4721499 (+) GRCh38	glioblastoma heroin dependence nicotine dependence opiate dependence	P32121 (UniProt | EBI) NM_001257331 (RefSeq)
mouse	Arrb2	MGI:99474 (MGI) 216869 (Entrez Gene) Gene Tree Arrb2 (Alliance of Genome Resources)	Chr11 42.99 cM	Chr11:70323461-70331654 (+) GRCm39		ENSMUSG00000060216 (Ensembl Gene Model) ENSMUSP00000104208 (Ensembl) ENSMUST00000108568 (Ensembl)
rat	Arrb2	RGD:2157 (Rat Genome Database) 25388 (Entrez Gene) Arrb2 (Alliance of Genome Resources)	Chr10 q24			P29067 (UniProt | EBI) NM_012911 (RefSeq)
zebrafish	arrb2a	ZDB-GENE-030131-29 (Zebrafish Model Organism Database) 321378 (Entrez Gene) arrb2a (Alliance of Genome Resources)	Chr10			NP_999846 (RefSeq) NM_214681 (RefSeq)
	arrb2b	ZDB-GENE-040426-1332 (Zebrafish Model Organism Database) 394099 (Entrez Gene) arrb2b (Alliance of Genome Resources)	Chr7			NP_957418 (RefSeq) NM_201124 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.